Publications

Publikationer rss feed

2021
 

In situ detection of protein interactions for recombinant therapeutic enzymes

Samoudi, Mojtaba ; Chung Kuo, Chih ; Robinson, Caressa M. ; Shams-Ud-Doha, Km ; Schinn, Song-Min ; Kol, Stefan ; Weiss, Linus ; Petersen Bjørn, Sara ; Voldborg, Bjørn G. ; Rosa Campos, Alexandre ; Lewis, Nathan E.
in: Biotechnology and Bioengineering

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    Year: 2021     |    DOI: https://doi.org/10.1002/bit.27621

2020
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A Markov model of glycosylation elucidates isozyme specificity and glycosyltransferase interactions for glycoengineering

Liang, Chenguang ; Chiang, Austin W. T. ; Hansen, Anders H. ; Arnsdorf, Johnny ; Schoffelen, Sanne ; Sorrentino, James T. ; Kellman, Benjamin P. ; Bao, Bokan ; Voldborg, Bjørn G. ; Lewis, Nathan E.
in: Current Research in Biotechnology, vol: 2, pages: 22-36

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1016/j.crbiot.2020.01.001

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Awakening dormant glycosyltransferases in CHO cells with CRISPRa

Julie la Cour Karottki, Karen ; Hefzi, Hooman ; Xiong, Kai ; Shamie, Isaac ; Hansen, Anders Holmgaard ; Li, Songyuan ; Pedersen, Lasse Ebdrup ; Li, Shangzhong ; Lee, Jae Seong ; Min Lee, Gyun ; Kildegaard, Helene Faustrup ; Lewis, Nathan E.
in: Biotechnology and Bioengineering, vol: 117, issue: 2, pages: 593-598

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1002/bit.27199

 

Comprehensive Analysis of Genomic Safe Harbors as Target Sites for Stable Expression of the Heterologous Gene in HEK293 Cells

Shin, Seunghyeon ; Kim, Su Hyun ; Shin, Sung Wook ; Grav, Lise Marie ; Pedersen, Lasse Ebdrup ; Lee, Jae Seong ; Lee, Gyun Min
in: ACS Synthetic Biology, vol: 9, issue: 6, pages: 1263-1269

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1021/acssynbio.0c00097

 

Elucidate Glycosyltransferase Specificities And Interactions for Rational Glycoengineering

Liang, Chenguang ; Chiang, Austin ; Hansen, Anders H. ; Arnsdorf, Johnny ; Schoffelen, Sanne ; Sorrentino, James ; Kellman, Benjamin ; Bao, Bokan ; Voldborg, Bjørn G. ; Lewis, Nathan
in: FASEB Journal, vol: 34, issue: S1

Type: Conference abstract in journal (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1096/fasebj.2020.34.s1.06683

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Enrichment of microsomes from Chinese hamster ovary cells by subcellular fractionation for its use in proteomic analysis

Pérez-Rodriguez, Saumel ; de Jesús Ramírez-Lira, María ; Wulff, Tune ; Voldbor, Bjørn Gunnar ; Ramírez, Octavio T. ; Trujillo-Roldán, Mauricio A. ; Valdez-Cruz, Norma A.
in: PLOS ONE, vol: 15, issue: 8

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1371/journal.pone.0237930

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Evolution-guided engineering of small-molecule biosensors

Snoek, Tim ; Chaberski, Evan Kirk ; Ambri, Francesca ; Kol, Stefan ; Bjørn, Sara P ; Pang, Bo ; Barajas, Jesus F ; Welner, Ditte Hededam ; Jensen, Michael Krogh ; Keasling, Jay D.
in: Nucleic acids research, vol: 48, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1093/nar/gkz954

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Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion

Gutierrez, Jahir M ; Feizi, Amir ; Li, Shangzhong ; Kallehauge, Thomas B ; Hefzi, Hooman ; Grav, Lise Marie ; Ley, Daniel ; Baycin Hizal, Deniz ; Betenbaugh, Michael J ; Voldborg, Bjørn Gunnar ; Kildegaard, Helene Faustrup ; Min Lee, Gyun ; Palsson, Bernhard O ; Nielsen, Jens ; Lewis, Nathan E
in: Nature Communications, vol: 11, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1038/s41467-019-13867-y

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High throughput generation of a resource of the human secretome in mammalian cells

Tegel, Hanna ; Dannemeyer, Melanie ; Kanje, Sara ; Sivertsson, Åsa ; Berling, Anna ; Svensson, Anne Sophie ; Hober, Andreas ; Enstedt, Henric ; Volk, Anna Luisa ; Lundqvist, Magnus ; Moradi, Mona ; Afshari, Delaram ; Ekblad, Siri ; Xu, Lan Lan ; Westin, Malin ; Bidad, Faranak ; Schiavone, Lovisa Holmberg ; Davies, Rick ; Mayr, Lorenz M. ; Knight, Sinead ; Göpel, Sven O. ; Voldborg, Björn G. ; Edfors, Fredrik ; Forsström, Björn ; von Feilitzen, Kalle ; Zwahlen, Martin ; Rockberg, Johan ; Takanen, Jenny Ottosson ; Uhlén, Mathias ; Hober, Sophia
in: New Biotechnology, vol: 58, pages: 45-54

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1016/j.nbt.2020.05.002